- Recommendation ID
- NG42/5
- Question
Nutrition:- Does a high calorific diet prolong survival of people with motor neurone disease (MND) if initiated following diagnosis or following initiation of feeding using a gastrostomy?
- Any explanatory notes
(if applicable) Why this is important:- There is little specific guidance on the optimal calorie intake for people with MND. There is growing evidence that people with MND have a hypercatabolic state and have high energy requirements. A large cohort study in the UK has demonstrated that nearly half of people continue to lose weight following gastrostomy and most show no improvement in their weight. A small study has emonstrated that high fat and high carbohydrate feeding may prolong survival in gastrostomy-fed people. A larger randomised trial is needed to inform clinical practice.
Source guidance details
- Comes from guidance
- Motor neurone disease: assessment and management
- Number
- NG42
- Date issued
- February 2016
Other details
| Is this a recommendation for the use of a technology only in the context of research? | No |
| Is it a recommendation that suggests collection of data or the establishment of a register? | No |
| Last Reviewed | 29/02/2016 |